The Brighton shop is one of 530 BHF clothing and accessory shops across the UK.
Each item sold in BHF shops will help to raise money to transform the lives of around 21,500 people from Brighton and Hove living with heart and circulatory diseases.
With around 20,946 people in the South East devastatingly losing their lives to conditions including heart disease, stroke and heart failure every year the charity say it is essential to accelerate research in to new treatments.
Fay Elms, the Area Manager for the BHF's Brighton Western Road shop said:
"We are really excited to see shoppers from Brighton injecting their own fashion flair in to our vast range of high quality donated clothes and accessories.
"Why wait to get started on your Big Stitch project, pop down to the BHF Brighton Western Road shop now to start getting crafty.
"Not only will you be creating a truly unique piece for your wardrobe, but all items bought from BHF shops go towards funding research into some of the UK"s biggest killers including heart disease and stroke."
From dresses to skirts and shirts, BHF shops provide a large range of quality clothing and accessories which can be turned into bespoke items at affordable prices, with all profits going towards the BHF's life saving heart research.
The Big Stitch competition* runs until 15th July 2018. Entrants are encouraged to tag the BHF in their "before" and "after" pictures on Twitter, Instagram or Facebook, using the hashtag #TheBigStitch.
All entries will be automatically entered into The Big Stitch competition and be in with a chance of winning one of the following prizes: return flights to a top European fashion destination, a Janome 2200XT sewing machine from Sew Essential or a £50 voucher towards a dressmaking class with Sew Over It. A winner will be selected and announced on 3rd August 2018.
The Brighton BHF shop is located at 140b Western Road, Brighton. Tel: 01273 746111.
For further information on The Big Stitch and information about how to locate your nearest BHF shop, please visit www.bhf.org.uk/TheBigStitch