The charity has produced a series of seven short animations, narrated by Reeves and featuring some of Andreae's best loved characters by his alter ego Edward Monkton, to add a little light to January.
The animations are being released on social media as Samaritans declares Monday 16th January, Brew Monday
, rather than Blue Monday, sometimes called "the most depressing day of the year".
The 20-second videos will bring us all a little cheer and the Brew Monday campaign will encourage friends, colleagues, neighbours and family members to share what's on their mind.
Samaritans' Lynsey Pollard said:
"People struggling alone with difficult thoughts often tell us they wish someone would notice what they are going through but they don't know how to explain or reach out for support.
"'Let us be kind' as Edward Monkton puts it in one of these beautiful animations and make Brew Monday a day when we all have that little bit of extra courage, to talk and to take time to listen to people we care about. It really could save a life."
A big fan of a timely brew, Vic Reeves (real name Jim Moir) is leading by example and combining his surreal sense of humour with Giles Andreae's work, which encourages us all to see things differently.
Giles Andreae, who has written publicly about his experience of depression said:
"If depression has taught me one thing, it is this: what a rare and beautiful treasure is the simple human gift of joy.
"For me now, joy - our capacity to delight in one another and in the world - is the reason why we are here. It is as simple as that. And I feel compelled to spread the word."