The auction will include a range of donated artwork from professional local, national and celebrity artists, illustrators and photographers, as well as some of the young people cared for by the hospice.
One highlight for 2016 is The Art Bird by the immensely popular Sussex-based children's illustrator Sir Quentin Blake.
Sir Quentin says, "As a children's book illustrator I'm particularly pleased to be able to support this wonderful children's charity in this way and I hope that my contribution will enable them to continue their invaluable support for so many families."
Other celebrity artists include: Downton Abbey star Hugh Bonneville whose donation was entitled Love, singer Gregory Porter who donated a drawing titled Don't Lose Your Steam", former star of TV"s The Bill, Chris Ellison, who donated a piece of work called Landscape, Julie Graham (At Home with the Braithwaites and William and Mary) who donated a drawing titled Smudge Says Have a Heart. Shoreham-based actress and comedian Carol Cleveland, best known from Monty Python, created a picture called Fairy Queen..
Andrew Comben, Chief Executive of Brighton Dome & Brighton Festival, says,
"To see people's creative flair translate into funds that help support local charities is a great thing.
"We are so grateful to the artistic community for supporting the event by donating their works."
The inaugural auction in 2015 was a huge success raising over £30,000 with a number of celebrity donations, which included a Tony Ross picture given by David Walliams.
On donating, Walliams said:
"I saw first-hand the amazing work the hospice does caring for children with life-shortening conditions and their families when I was privileged enough to visit the house and read to the children.
"I know that the funds raised from the auction will make a real difference to children and their families across Sussex."
The Big Heart Auction @ Brighton Dome Founders Room 1-5 July 2016. All the works will be available to purchase via the online auction on EBay running from 1-10 July and you can view them all online at www.bigheartauction.org.uk.